TDRD12 Antibody - Cat. #: CSB-PA707440LA01HU

SKU: CSB-PA707440LA01HU

Size :50ug

Clone Number:

Aliases:ECAT8 antibody; ES cell associated transcript 8 antibody; ES cell-associated transcript 8 protein antibody; TDR12_HUMAN antibody; Tdrd12 antibody; Tudor domain containing 12 antibody; Tudor domain-containing protein 12 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q587J7

Immunogen:Recombinant Human Putative ATP-dependent RNA helicase TDRD12 protein (991-1164AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TDRD12

Research Areas:Epigenetics and Nuclear Signaling