TDGF1 Monoclonal Antibody

SKU: BT-MCA3391

Size:100μL

Background:This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.

Research_area:Developmental biology, Stem cells

Target_protein:TDGF1

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:3A6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:TDGF1

Immunogen:Purified recombinant fragment of human TDGF1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):21kDa

UniProt accession:P13385

Synonyms:CR, CRGF, CRIPTO, TDGF1

GeneID:6997