TALPID3 antibody , Cat. # FNab08496

SKU: FNab08496

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Required for ciliogenesis and sonic hedgehog/SHH signaling(PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation(By similarity). Involved in regulation of cell intracellular organization(PubMed:26386247). Involved in regulation of cell polarity(By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles(PubMed:25251415).

Immunogen:KIAA0586

Synonyms:

Observed MW:

Uniprot ID:E9PV87

Reactivity:Human, Mouse

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:50-1:500

Gene ID:76967

Research Area: