STK24 Antibody, Biotin conjugated - Cat. #: CSB-PA00249D0Rb

SKU: CSB-PA00249D0Rb

Size :50ug

Clone Number:

Aliases:epididymis secretory protein Li 95 antibody; HEL-S-95 antibody; Mammalian STE20 like protein kinase 3 antibody; Mammalian STE20-like protein kinase 3 antibody; Mammalian STE20-like protein kinase 3 C-terminal antibody; Mammalian STE20-like protein kinase 3 N-terminal antibody; Mammalian sterile 20-like 3 antibody; MST-3 antibody; MST3/C antibody; MST3/N antibody; MST3B antibody; serine threonine kinase 24 antibody; Serine/threonine kinase 24 (Ste20; yeast homolog) antibody; Serine/threonine-protein kinase 24 12 kDa subunit antibody; Serine/threonine-protein kinase 24 antibody; STE20 homolog yeast antibody; STE20 like kinase MST3 antibody; STE20-like kinase MST3 antibody; Stk24 antibody; STK24_HUMAN antibody; STK3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y6E0

Immunogen:Recombinant Human Serine/threonine-protein kinase 24 protein (1-431AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on \'Thr-442\' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:STK24

Research Areas:Signal transduction