STAT6 Polyclonal Antibody

SKU: E-AB-10059

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: STAT6

Target Synonym: 12S1644;D12S1644;IL 4 STAT;IL-4 Stat;IL4 STAT;Interleukin 4 Induced;Interleukin 4 Induced Transcription Factor IL4 STAT;Signal transducer and activator of transcription 6;Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced;Signal Transducer And Activator Of Transcription 6 Nirs Variant 1;Signal transducer and activator of transcription 6;interleukin 4 induced;STAT 6;STAT interleukin4 induced;STAT;interleukin4 induced;Stat6;STAT6;STAT6B;STAT6C;Transcription factor IL 4 STAT

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P42226

Accession:

Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human STAT6

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 94kDa

ObservedMW: