Sp1(Phospho Thr453) Polyclonal Antibody

SKU: BT-AP14389

Size:100μL

Background:The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and nuclear signaling; Stem cells; Metabolism

Target_protein:SP1

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Transcription factor Sp1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):80693

UniProt accession:Human: P08047; Mouse: O89090; Rat: Q01714

Synonyms:Transcription factor Sp1; SP1; TSFP1; Transcription factor Sp1

GeneID:Human: 6667; Mouse: 20683; Rat: 24790