SOD1 Polyclonal Antibody

SKU: BT-AP14363

Size:100μL

Background:The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Research_area:Signal transduction; Cell biology; Metabolism; Cancer

Target_protein:SOD1

applications:WB, IHC-p, IF

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Superoxide dismutase [Cu-Zn]

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P00441; Mouse: P08228; Rat: P07632

Synonyms:Superoxide dismutase [Cu-Zn]; SOD1; Superoxide dismutase [Cu-Zn; ; Superoxide dismutase 1; hSod1

GeneID:Human: 6647