SMOX Rabbit Polyclonal Antibody

SKU: BT-AP04789

Size:100μL

Background:Polyamines are ubiquitous polycationic alkylamines which include spermine| spermidine| putrescine| and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation| scavenging reactive oxygen species| and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity| involvement in intracellular signalling pathways| and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene| some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities| suggesting the existence of additional levels of complexity in polyamine catabolism.

Research_area:Signal transduction; Metabolism

Target_protein:SMOX

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:SMOX

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):61050

UniProt accession:Human: Q9NWM0; Mouse: Q99K82

Synonyms:SMOX

GeneID:Human: 54498; Mouse: 228608