SIRT2 Monoclonal Antibody

SKU: BT-MCA3539

Size:100μL

Background:This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]

Research_area:Epigenetics and Nuclear Signaling

Target_protein:SIRT2

applications:

Reactivity:

Clonality:Monoclonal

Clone ID:5H11H9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SIRT2

Immunogen:Purified recombinant fragment of human SIRT2 (AA: 275-389) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):43.2kDa

UniProt accession:Q8IXJ6

Synonyms:SIR2, SIR2L, SIR2L2

GeneID:22933