SIGIRR Antibody - Cat. #: CSB-PA743558ESR1HU

SKU: CSB-PA743558ESR1HU

Size :50ul

Clone Number:

Aliases:Ig IL1 related receptor antibody; MGC110992 antibody; SIGIR_HUMAN antibody; SIGIRR antibody; Single Ig IL 1 related receptor antibody; Single Ig IL-1-related receptor antibody; Single Ig IL-1R-related molecule antibody; Single Ig IL1R Related Molecule antibody; Single immunoglobulin and toll interleukin 1 receptor (TIR) domain antibody; Single immunoglobulin and toll interleukin 1 receptor domain antibody; Single immunoglobulin domain containing IL1R related protein antibody; Single immunoglobulin domain IL1R1 related antibody; Single immunoglobulin domain-containing IL1R-related protein antibody; TIR 8 antibody; TIR8 antibody; Toll/interleukin 1 receptor 8 antibody; Toll/interleukin-1 receptor 8 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6IA17

Immunogen:Recombinant Human Single Ig IL-1-related receptor protein (1-120AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SIGIRR

Research Areas:Immunology; Signal transduction