SH2B2 Monoclonal Antibody

SKU: BT-MCA4598

Size:100μL

Background:The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Research_area:Others

Target_protein:SH2B2

applications:IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5E11G7

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:SH2B2

Immunogen:Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):67.7kDa

UniProt accession:O14492

Synonyms:APS

GeneID:10603