SEMA4A Antibody - Cat. #: CSB-PA954171

SKU: CSB-PA954171

Size :50ul

Clone Number:

Aliases:CORD10 antibody; RP11 54H19 2 antibody; RP35 antibody; SEM4A_HUMAN antibody; Sema B antibody; Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain 4A antibody; Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4A antibody; Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) antibody; Sema4a antibody; SEMAB antibody; Semaphorin 4A precursor antibody; Semaphorin B antibody; Semaphorin-4A antibody; Semaphorin-B antibody; SEMB antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H3S1

Immunogen:Fusion protein of Human SEMA4A

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:30-1:150

Background:This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SEMA4A

Research Areas:Neuroscience;Cardiovascular