RUBCN Monoclonal Antibody

SKU: BT-MCA4352

Size:100μL

Background:The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research_area:Others

Target_protein:RUBCN

applications:

Reactivity:

Clonality:Monoclonal

Clone ID:4F5B5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:RUBCN

Immunogen:Purified recombinant fragment of human NR2C2 (AA: 62-356) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):108.6kDa

UniProt accession:Q92622

Synonyms:SCAR15, RUBICON, KIAA0226

GeneID:9711