RSAD2 Antibody - Cat. #: CSB-PA848838ESR1HU

SKU: CSB-PA848838ESR1HU

Size :50ul

Clone Number:

Aliases:2510004L01Rik antibody; cig 33 antibody; CIG 5 antibody; cig-33 antibody; CIG-5 antibody; CIG33 antibody; CIG5 antibody; Cytomegalovirus induced gene 5 protein antibody; Cytomegalovirus-induced gene 5 protein antibody; endoplasmic reticulum-associated antibody; interferon-inducible antibody; Radical S adenosyl methionine domain containing 2 antibody; Radical S-adenosyl methionine domain-containing protein 2 antibody; RSAD 2 antibody; Rsad2 antibody; RSAD2_HUMAN antibody; RSDA-2 antibody; VIG 1 antibody; vig1 antibody; Viperin antibody; Virus inhibitory protein antibody; virus inhibitory protein endoplasmic reticulum associated interferon inducible antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8WXG1

Immunogen:Recombinant Human Radical S-adenosyl methionine domain-containing protein 2 protein (42-361AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63\\\'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RSAD2

Research Areas:Others