RRAGA/RRAGB Antibody - Cat. #: CSB-PA590465

SKU: CSB-PA590465

Size :100ul

Clone Number:

Aliases:Adenovirus E3 14.7 kDa-interacting protein 1 antibody; FIP-1 antibody; Rag A antibody; RagA antibody; Ras-related GTP-binding protein A antibody; RRAGA antibody; RRAGA_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q7L523

Immunogen:Synthesized peptide derived from internal of Human RRAGA/B.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Schuermann A., J. Biol. Chem. 270:28982-28988(1995).
Li Y., J. Virol. 71:1576-1582(1997).
Hirose E., J. Cell Sci. 111:11-21(1998).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RRAGA/RRAGB

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Metabolism?Microbiology?Signal transduction