RPRD1B Monoclonal Antibody

SKU: AN200235P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:RPRD1B

Target Synonym:NET;C20orf;dJ1057B;RPRD1B;C20orf77;CREPT;NET60;dJ1057B20.2;K-H;Kub5-Hera

Research Areas:Cell Biology

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:ICC/IF

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:2D9

UNIProt ID:Q9NQG5

Accession:

Background:Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

Concentration:1 mg/mL

Immunogen:Recombinant Human RPRD1B Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:20-1:100

Calculated MW:

ObservedMW: