RNLS Antibody - Cat. #: CSB-PA726123ESR1HU

SKU: CSB-PA726123ESR1HU

Size :50ul

Clone Number:

Aliases:6530404N21Rik antibody; AI452315 antibody; AW060440 antibody; C10orf59 antibody; Chromosome 10 open reading frame 59 antibody; FLJ11218 antibody; HGNC:25641 antibody; Hypothetical protein LOC55328 antibody; MAO C antibody; MAO-C antibody; mMAO C antibody; Monoamine oxidase C antibody; Monoamine oxidase-C antibody; Renalase antibody; Renalase FAD dependent amine oxidase antibody; RNLS antibody; RNLS_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q5VYX0

Immunogen:Recombinant Human Renalase protein (18-342AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RNLS

Research Areas:Neuroscience; Cardiovascular