Recombinant YY1 Monoclonal Antibody

SKU: E-AB-81623

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:YY1

Target Synonym:CF1;Delta;Delta transcription factor;INO80 complex subunit S;INO80S;NF E1;NF-E1;NFE1;OTTHUMP00000197459;Transcriptional repressor protein YY1;TYY1;UCR motif DNA binding protein;UCRBP;Yin and yang 1;Yin and Yang 1 protein;Yin Yang 1;Ying Yang 1;YY 1;YY 1 transcription factor;YY-1;YY1;YY1 transcription factor

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R02-8A3

UNIProt ID:P25490

Accession:

Background:YY1,also named as DELTA,INO80S and NF-E1,contains four C2H2-type zinc fingers and belongs to the YY transcription factor family. YY1 is a multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter,thus implicating histone modification in the YY1. The open reading frame of the human YY1 cDNA encodes a protein of 414 amino acids with a predicted molecular weight of 44 kDa. However,YY1 migrates on SDS gels as a 65–68 kDa protein,probably due to the structure of the protein. It is a ubiquitously expressed transcription factor with fundamental roles in embryogenesis,differentiation,replication and proliferation.

Concentration:300 μg/mL

Immunogen:A synthetic peptide of human YY1

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:1000-1:2000

Calculated MW:45kDa

ObservedMW:65kDa