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GeneBio Systems

Recombinant WT1 Monoclonal Antibody

Recombinant WT1 Monoclonal Antibody

AN302022L

€349,95 EUR
€349,95 EUR
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:WT1

Target Synonym:AWT;FWT;NPHS;EWS-WT;WIT;WT1;AWT1;EWS-WT1;GUD;NPHS4;WAGR;WIT-2;WT33;FWT1;Wilms Tumor;Wilms tumor 1;Wilms' tumor gene;Wilms tumor protein;Wilms' tumor protein;WIT 2;WIT2;WT;WT 1;WIT 2; WT 1;AWT1;FWT1;GUD;NPHS4;WAGR;Wilms tumor 1;Wilms Tumor;Wilms tumor protein;Wilms' tumor gene;Wilms' tumor protein;WIT2;WT;WT1;WT1;WT33

Research Areas:Tags & Cell Markers;Epigenetics and Nuclear Signaling;Cancer;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A742

UNIProt ID:P19544

Accession:

Background:Wilms' Tumor protein (WT1) is a transcription factor named from Wilms' Tumor 1, an embryonal malignancy of the kidneys that is caused by mutations in the WT1 gene. It is highly important in development, particularly of the genitourinary system, and mutations and dysregulation of expression of WT1 result in a variety of syndromes affecting the genitourinary system and other tissues.WT1 has a myriad of biological functions and a host of interacting partners and target genes. It can behave as a transcriptional activator, or a repressor, and can act as an oncogene or a tumor suppressor. It exerts influence over the epigenetic landscape, and also has post translational influence of gene expression through RNA interactions. The diverse biological roles of WT1 have been attributed to the existence of multiple isoforms and post translation modifications of the protein.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:2000-1:10000;IHC 1:100

Calculated MW:49 kDa

ObservedMW:52 kDa

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