Recombinant WHSC1 Monoclonal Antibody

SKU: AN301885L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:WHSC1

Target Synonym:TRX;NSD;WHSC;KIAA;NSD2;KMT3F;KMT3G;MMSET;REIIBP;TRX5;WHS;WHSC1;KIAA1090

Research Areas:Epigenetics and Nuclear Signaling;Tags & Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A601

UNIProt ID:O96028

Accession:

Background:WHSC1, also known as MMSET or NSD2, is a SET domain containing histone lysine methyltransferase that can di- and trimethylate histone H3 at lysine 36 (H3K36). WHSC1 mRNA is highly expressed in embryonic tissues, especially those with high degrees of proliferation, whereas in adult tissues, the mRNA is primarily expressed in thymus and testis. WHSC1 is implicated in cellular adhesion, clonogenic growth and tumorigenicity. Its overexpression has been found in various cancers. It undergoes alternative splicing resulting in different protein isoforms. Recently WHSC1 has been identified as a critical epigenetic regulator for Tfh differentiation.

Concentration:1 mg/mL

Immunogen:Recombinant human WHSC1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:5000

Calculated MW:153 kDa

ObservedMW:153 kDa