Recombinant Vitamin D Receptor Monoclonal Antibody

SKU: AN302069L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Vitamin D Receptor

Target Synonym:NR1I;nuclear receptor subfamily;PPP1R;member;VDR;NR1I1;PPP1R163;group I;member 1;nuclear receptor subfamily 1;vitamin D receptor

Research Areas:Epigenetics and Nuclear Signaling;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A789

UNIProt ID:P11473

Accession:

Background:This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:3000;IP 1:50-1:100

Calculated MW:48 kDa

ObservedMW:48 kDa