Recombinant TMEM173 Monoclonal Antibody

SKU: AN301084L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:TMEM173

Target Synonym:NET;TMEM;TMEM173;ERIS;MITA;MPYS;NET23;SAVI;STING;hMITA;hSTING;Mediator of IRF3 activation;Stimulator of interferon genes protein;STING1;endoplasmic reticulum IFN stimulator;Endoplasmic reticulum interferon stimulator;FLJ38577;Mitochondrial mediator of IRF3 activation;N terminal methionine proline tyrosine serine plasma membrane tetraspanner;Stimulator of interferon genes;TM173;Transmembrane protein 173

Research Areas:Immunology;Signal Transduction;Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6G8

UNIProt ID:Q86WV6

Accession:

Background:This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human TMEM173 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1000;WB 1:1000-5000

Calculated MW:42 kDa

ObservedMW:37 kDa