Recombinant Tissue Factor Monoclonal Antibody

SKU: E-AB-81613

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:Tissue Factor

Target Synonym:CD142;CD142 antigen;Coagulation factor III (thromboplastin tissue factor);Coagulation factor III;F3;FLJ17960;TF;TF;TFA;Thromboplastin;Tissue factor

Research Areas:Cancer;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R04-7G2

UNIProt ID:P13726

Accession:

Background:This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Concentration:300 μg/mL

Immunogen:A synthetic peptide of human Tissue Factor

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:1000-1:2000;IHC 1:50-1:100

Calculated MW:33kDa

ObservedMW:45kDa