Recombinant TAK1 Monoclonal Antibody

SKU: AN300959L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Tak1

Target Synonym:TAK;FMD;MEKK;MAP3K;CSCF;FMD2;MEKK7;TAK1;TGF1a;MAP3K7;M3K7;MAP3K 7;Mitogen activated protein kinase kinase kinase 7;Mitogen-activated protein kinase kinase kinase 7;TGF beta activated kinase 1;TGF-beta-activated kinase 1;Transforming growth factor beta activated kinase 1;Transforming growth factor-beta-activated kinase 1

Research Areas:Signal Transduction;Cancer;Cardiovascular;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5F7

UNIProt ID:O43318

Accession:

Background:The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human TAK1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000;

Calculated MW:67 kDa

ObservedMW:67 kDa