GeneBio Systems
Recombinant SH-PTP2 Monoclonal Antibody
Recombinant SH-PTP2 Monoclonal Antibody
SKU:AN300806L
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Size::50μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:Ice bag
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Recombinant Antibodies;Monoclonal Antibodies
Abbreviation:SH-PTP2
Target Synonym:SHP;PTN;SAP;BPTP;PTPN;BPTP3;CFC;JMML;METCDS;NS1;PTP-1D;PTP2C;SH-PTP2;SH-PTP3;SHP2;PTPN11;PTN11;SAP2;SHPTP3;Syp;SHPTP2;MGC14433;OTTHUMP00000166107;OTTHUMP00000166108;Protein tyrosine phosphatase 2;Protein tyrosine phosphatase 2C;Protein tyrosine phosphatase non receptor type 11;Protein-tyrosine phosphatase 1D;Protein-tyrosine phosphatase 2C;PTP1D;PTP2-C;PTP-2C;SH2 domain containing protein tyrosine phosphatase 2;SHP 2;SHP-2;Syp;Tyrosine-protein phosphatase non-receptor type 11
Research Areas:Signal Transduction;Neuroscience
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human;Mouse;Rat
Application:WB
Isotype:IgG,κ
Clonality:Monoclonal;Recombinant
Clone NO.:4B5
UNIProt ID:Q06124
Accession:
Background:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Concentration:0.2 mg/mL
Immunogen:Recombinant Human SH-PTP2 protein
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Purification method:Protein A
Dilution:WB 1:2000-1:10000
Calculated MW:68 kDa
ObservedMW:68 kDa
