Recombinant S100A4 Monoclonal Antibody

SKU: E-AB-81606

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:S100A4

Target Synonym:18A2;42A;calcium Placental protein;Calvasculin;CAPL;Fibroblast specific protein 1 (FSP1);Fibroblast specific protein 1;Fibroblast specific protein;FSP1;Leukemia multidrug resistance associated protein;Malignant transformation suppression 1 (MTS1);Malignant transformation suppression 1;Metastasin;MTS1;OTTHUMP00000015467;OTTHUMP00000015468;P9KA;PEL98;Placental calcium-binding protein;Protein Mts1;Protein S100 A4;Protein S100-A4;S100 calcium binding protein A4 (calcium protein;calvasculin;metastasin;murine placental homolog);S100 calcium binding protein A4;S100 calcium-binding protein A4;S100a4;S10A4

Research Areas:Cancer;Cardiovascular;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC-P;IF

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R01-7H1

UNIProt ID:P26447

Accession:

Background:S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.

Concentration:300 μg/mL

Immunogen:A synthetic peptide of human S100A4

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:1000-1:2000;IHC 1:50-1:100

Calculated MW:12kDa

ObservedMW:12kDa