Recombinant Rat MCP-3/CCL7 protein

SKU: CD00092

Size:2 ug

Background:Rat CCL7, belonging to the CC chemokine family, is also named as MCP-3, because the sequence comparison suggested that the rat CCL7 is a homologue of the human MCP-3 and is postulated the rat MCP-3. The MCP-3 protein family signals through CCR2 expect MCP-1 and possess cross-reacts across species. CCL7/MCP3 has chemotactic functions for monocytes and eosinophils, but not for neutrophils. Additionally, it can activated NK cells as well as CD4+ and CD8+ T lymphocytes. CCL7 was found to interact with MMP2.

Research_area:Immunology

Purity:> 95 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Rat Monocyte Chemotactic Protein-3/CCL7

Biological activity:Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1-1 ng/ml.

Synonyms:MCP-3/CCL7, Scya17, Tarc,Rat

Endotoxin:Less than 1 EU/μg of rRtMCP-3/CCL7 as determined by LAL method.

Storage:-20ºC

Sequence:QPDGTNSSTC CYVKKQKIPK RNLKSYRKIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTS TPKP

uniprot accession:Q9QXY8

Molecular weight:Approximately 8.5 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 × PBS, pH 7.4.