Recombinant Pig Lactadherin (MFGE8)

SKU: P79385

Size: 100ug. Other sizes are also available.

Activity: Not tested

Research Areas: Cardiovascular

Uniprot ID: P79385

Gene Names: MFGE8

Alternative Name(s): MFGM;Milk fat globule-EGF factor 8;MFG-E8;SED1;Sperm surface protein SP47;PP47

Abbreviation: Recombinant Pig MFGE8 protein

Organism: Sus scrofa (Pig)

Source: E.coli

Expression Region: 1-409aa

Protein Length: Full Length

Tag Info: C-terminal 6xHis-tagged

Target Protein Sequence: FSGDFCDSSLCLNGGTCLLDQDPQKPFHCLCPEGFTGLICNETEKGPCFPNPCHNDAECEVIDDAHRGDVFTEYICKCPHGYTGIHCEIICNAPLGMETGAIADFQISASSMHLGFMGLQRWAPELARLHRAGIVNAWTASNYDRNPWIQVNLLRRMRVTGVVTQGASRAGSAEYMKTFKVAYSTDGRKFQFIQGAEESGDKIFMGNLDNSGLKVNLFEVPLEVQYVRLVPIICHRGCTLRFELLGCELSGCAEPLGLKDNTIPNKQITASSFYRTWGLSAFSWYPFYARLDNQGKFNAWTAQSNSASEWLQIDLGSQRRVTGIITQGARDFGHIQYVAAYKVAYSDDGVSWTEYRDQGALEGKIFPGNLDNNSHKKNMFETPFLTRFVRILPVAWHNRITLRVELLGC

MW: 52.6 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Endotoxin: Not test

Biological_Activity:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Relevance: Contributes to phagocytic removal of apoptotic cells in many tissues. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction.

Reference:

Function: