Recombinant PI3 Kinase p110 alpha Monoclonal Antibody

SKU: AN301630L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:PI3 Kinase p110 alpha

Target Synonym:CWS;PIK3CA;CLOVE;CWS5;MCAP;MCM;MCMTC;PI3K;PI3K-alpha;5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha;5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha;5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha;5-bisphosphate 3-kinase catalytic subunit alpha isoform;caPI3K;MGC142161;MGC142163;p110 alpha;p110alpha;Phosphatidylinositol 3 kinase catalytic 110 KD alpha;Phosphatidylinositol 3 kinase catalytic alpha polypeptide;Phosphatidylinositol 4;Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha;Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform;Phosphatidylinositol-4;Phosphoinositide 3 kinase catalytic alpha polypeptide;Phosphoinositide 3-kinase alpha;Phosphoinositide-3-kinase catalytic alpha polypeptide;PI3 kinase p110 subunit alpha;PI3Kalpha;PI3KC A;PI3-kinase subunit alpha;PIK3C A;PK3CA;PtdIns 3 kinase p110;PtdIns-3-kinase subunit alpha;PtdIns-3-kinase subunit p110-alpha;Serine/threonine protein kinase PIK3CA

Research Areas:Signal Transduction;Cancer;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A333

UNIProt ID:P42336

Accession:

Background:Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.

Concentration:1 mg/mL

Immunogen:Recombinant human PI3 Kinase p110 alpha fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:50

Calculated MW:110 kDa

ObservedMW:120 kDa