Recombinant Phospho-Smad3 (Ser423, Ser425) Monoclonal Antibody

SKU: AN301148L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Smad3

Target Synonym:LDS;MAD;HSPC;JV15;MADH;MAD homolog;SMAD family member;Mothers against DPP homolog;Mothers against decapentaplegic homolog;hMAD;hSMAD;HSPC193;HsT17436;JV15-2;LDS1C;LDS3;MADH3;hMAD-3;hSMAD3;MAD homolog 3;Mad3;Mothers against decapentaplegic homolog 3;Mothers against DPP homolog 3;SMAD 3;SMAD family member 3;SMAD3;DKFZP586N0721;DKFZp686J10186;hMAD 3;JV15 2;JV152;MAD (mothers against decapentaplegic Drosophila) homolog 3;Mad homolog JV15 2;Mad protein homolog;MADH 3;MGC60396;SMA and MAD related protein 3;SMAD

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Stem Cells;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6H9

UNIProt ID:P84022

Accession:

Background:The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Ser423, Ser425) of Human Phospho-Smad3

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:2000-1:10000

Calculated MW:48 kDa

ObservedMW:52 kDa