Recombinant p40 Monoclonal Antibody

SKU: AN301961L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:p40

Target Synonym:RAB9P;RAB9P40;RABEPK;40 kDa Rab9 effector protein;8430412M01Rik;9530020d24rik;AV073337;bA65N13.1;C87311;DKFZp686P1077;OTTHUMP00000022126;OTTMUSP00000012898;OTTMUSP00000012899;OTTMUSP00000041318;p40;RAB9 effector p40;Rab9 effector protein with Kelch motifs;RABEK;RABEPK protein;RGD1310612;RP11 65N13.1;RP23-446N16.2

Research Areas:Signal Transduction;Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A677

UNIProt ID:Q7Z6M1

Accession:

Background:Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.

Concentration:1 mg/mL

Immunogen:Recombinant human p40 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:2000

Calculated MW:41 kDa

ObservedMW:41 kDa