Recombinant MTF2 Monoclonal Antibody

SKU: AN302036L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:MTF2

Target Synonym:PCL;MTF;dJ976O;MTF2;M96;PCL2;TDRD19A;dJ976O13.2;hPCl2;metal regulatory transcription factor 2;Metal response element binding transcription factor 2;metal-response element DNA-binding protein M96;polycomb-like 2;polycomb-like protein 2;Putative DNA binding protein;RP5 976O13.1;RP5-976O13.1;tudor domain containing 19A

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A756

UNIProt ID:Q9Y483

Accession:

Background:MTF2, also named as Metal-response element-binding transcription factor 2, is a 593 amino acid protein. It exists several isoforms and the range of the molecular weight of isoforms are about 55-60 kDa and 29 kDa. MTF2 contains 2 PHD-type zinc fingers and belongs to the Polycomblike family. MTF2 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity and regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000

Calculated MW:67 kDa

ObservedMW:47-67 kDa