Recombinant MRE11 Monoclonal Antibody

SKU: AN301268L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:MRE11

Target Synonym:MRE;HNGS;MRE11;ATLD;HNGS1;MRE11A;MRE11B;AT like disease;Ataxia telangiectasia disorder like;DNA recombination and repair protein;Double strand break repair protein MRE11A;Double-strand break repair protein MRE11A;endo/exonuclease Mre11;meiotic recombination (S. cerevisiae) 11 homolog A;Meiotic recombination 11 homolog 1;Meiotic recombination 11 homolog A;meiotic recombination 11 homolog A (S. cerevisiae);MmMRE11A;Mre 11;MRE 11a;MRE 11b;MRE11 homolog 1;MRE11 homolog A;MRE11 homolog double strand break repair nuclease;MRE11 meiotic recombination 11 homolog A;MRE11 meiotic recombination 11 homolog A (S. cerevisiae);OTTHUMP00000236830;OTTHUMP00000236831;OTTHUMP00000236832;OTTHUMP00000236833;MRE11

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6B9

UNIProt ID:P49959

Accession:

Background:This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human MRE11 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000

Calculated MW:

ObservedMW: