Recombinant Mouse IL2Ra/CD25 Protein (Fc Tag)

SKU: PKSM041228

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: IL2Ra;CD25

Target Synonym: IDDM;alpha;CD25;CD25 antigen;IDDM10;IL-2 R alpha;IL-2 receptor subunit alpha;IL-2R subunit alpha;IL2-RA;IL-2-RA;interleukin 2 receptor;Interleukin-2 receptor subunit alpha;Ly-43;p55;TAC antigen;TCGFR;Il2r;Il2ra;Tac; p55; Ly-43; IL-2R&alpha

Research Areas:

Conjugation:

Target Species: Mouse

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc

UNIProt ID:

Accession: P01590

Background: The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (γc). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.

Concentration:

Activity: Not validated for activity

Sequence: Glu22-Lys236

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 51.6 kDa

ObservedMW: 60-90 kDa