Recombinant Mouse Galectin-3/Lgals3 protein (His Tag)

SKU: PDEM100233

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:Galectin-3;Lgals3

Target Synonym:35 kDa lectin;CBP35;Carbohydrate binding protein 35;GAL3;GALBP;GALIG;GBP;Gal-3;IgE binding protein;LGALS2;Lectin L-29;Mac-2 antigen;Macrophage galactose-specific lectin

Research Areas:

Conjugation:

Target Species:Mouse

Expression Host:E.coli

Application:Immunogen

Fusion tag:N-His

UNIProt ID:P16110

Accession:P16110

Background:Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

Concentration:

Activity:Not validated for activity

Sequence:Ala2-Ile264

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:27.4 kDa

ObservedMW:31-33 kDa