Recombinant LEF1 Monoclonal Antibody

SKU: AN300698L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:LEF1

Target Synonym:TCF;TCF7L;LEF;LEF1;LEF-1;TCF10;TCF1ALPHA;TCF7L3;LEF-1

Research Areas:Epigenetics and Nuclear Signaling;Stem Cells;Cancer;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:10F14

UNIProt ID:Q9UJU2

Accession:

Background:This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human LEF1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:44 kDa

ObservedMW:45-60 kDa