Recombinant Lactate Dehydrogenase A Monoclonal Antibody

SKU: E-AB-81451

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:Lactate Dehydrogenase A

Target Synonym:Cell proliferation-inducing gene 19 protein;GSD11;L lactate dehydrogenase A chain;l7R2;LDH M;LDH muscle subunit;LDH1;PIG19 Proliferation-inducing gene 19

Research Areas:Cancer;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat

Application:WB

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R09-9A7

UNIProt ID:P00338

Accession:

Background:LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

Concentration:300 μg/mL

Immunogen:A synthetic peptide of human Lactate Dehydrogenase

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:1000-1:2000

Calculated MW:37kDa

ObservedMW:37kDa