Recombinant IL-5 Monoclonal Antibody

SKU: AN300285P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:IL5

Target Synonym:nterleukin;Interleukin;IL5;EDF;IL-5;TRF;BCDFII;B-cell differentiation factor I;B-cell growth factor I;BCGF-II;Cytotoxic T-lymphocyte inducer;E-CSF;Eosinophil differentiation factor;ESGF;Interleukin-5;nterleukin-5;T-cell replacing factor

Research Areas:Immunology;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Monoclonal

Clone NO.:10C8

UNIProt ID:P05113

Accession:

Background:This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

Concentration:1 mg/mL

Immunogen:Recombinant Human IL-5 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;

Calculated MW:15 kDa

ObservedMW:20 kDa