Recombinant Human Try-2 Protein(His Tag)

SKU: PDMH100327

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:Try-2

Target Synonym:PRSS;TRYP;Tesp;Serine protease;TRY2TRY;EC 3.4.;TRY;PRSS2;TRY2;TRY8;TRYP2;trypsin-2;serine;preproprotein;protease;MGC111183;Tesp4;MGC120174;TRY2TRY8;MGC120175;Anionic trypsinogen;2 (trypsin 2);EC 3.4.21;EC 3.4.21.4;Serine protease 2;protease serine 2 preproprotein;Trypsin 2;Trypsin II;trypsinogen 2;Trypsinogen 20

Research Areas:Signal Transduction;Metabolism;Cell Biology

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-His

UNIProt ID:P07478

Accession:P07478

Background:Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary for the uptake of protein in the food. It is secreted by the pancreas in the form of inactive zymogen, trypsinogen and cleaved to its active form in the small intestine when the pancreas is stimulated by cholecystokinin throμgh the common activation mechanism.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Ser247

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:27.1 kDa

ObservedMW:30 kDa