Recombinant Human TECK/CCL25 protein

SKU: CD00837

Size:5 ug

Background:CCL25 is new member of CC family chemokine. It is also called Thymus-expressed chemokine (TECK) because it is restricted produced by thymus and intestine. Especially, the dendritic cells derived from thymus but not bone marrow had identified to be the source of CCL25. By binding with CCR9, it elicits its effects of chemotactic for thymocytes, macrophages, and dendritic cells. Additionally, CCL25 takes part in regulating the development of T-cells.

Research_area:Immunology

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Thymus Expressed Chemokine/CCL25

Biological activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.-1 ng/ml.

Synonyms:CCL25, Ck beta-15, Ckb15, SCYA25, TECK,Human

Endotoxin:Less than 1 EU/μg of rHuTECK/CCL25 as determined by LAL method.

Storage:-20ºC

Sequence:MQGVFEDCCL AYHYPIGWAV LRRAWTYRIQ EVSGSCNLPA AIFYLPKRHR KVCGNPKSRE VQRAMKLLDA RNKVFAKLHH NTQTFQAGPH AVKKLSSGNS KLSSSKFSNP ISSSKRNVSL LISANSGL

uniprot accession:O15444

Molecular weight:Approximately 14.3 kDa, a single, non-glycosylated polypeptide chain containing 128 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 mM PB, pH 7.4, 15 mM NaCl.