Recombinant Human POSTN Protein (His Tag)

SKU: PDEH100684

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:POSTN

Target Synonym:Fasciclin-I like;MGC119510;MGC119511;OSF 2;OSF-2;OSF2;Osteoblast specific factor;Osteoblast specific factor 2;Osteoblast specific factor 2 (fasciclin I like);Osteoblast-specific factor 2;PDLPOSTN;Periodontal ligament specific periostin;Periostin

Research Areas:Signal Transduction,Tags & Cell Markers,Cancer,Cardiovascular

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-His

UNIProt ID:Q15063

Accession:Q15063-1

Background:Periostin (POSTN,PN),originally named as osteoblast-specific factor 2 (OSF-2),is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues,and has a role in bone,tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types,includidng lung,ovary,breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour,and it is required to allow cancer stem cell maintenance.

Concentration:

Activity:Not validated for activity

Sequence:Ala21-Leu365

Purity: > 85% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile 20mM Tris,1mM EDTA, pH 8.0
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:38 kDa

ObservedMW:40.3 kDa