Recombinant Human NRP2 Protein(hIgG1 Fc Tag)

SKU: PDMH100445

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:NRP2

Target Synonym:PRO;NPN;NRP;neuropilin;vascular endothelial growth factor-165 receptor;VEGF165R;NRP2;NP2;NPN2;PRO2714;VEGF165R2;neuropilin-2;vascular endothelial growth factor-165 receptor 2;MGC126574;Neuropilin 2;Neuropilin2;NP 2;NPN 2;NRP 2;Receptor for VEGF165 and semaphorins class3;Vascular endothelial cell growth factor 165 receptor 2;Vascular endothelial growth factor 165 receptor 2;VEGF1265R2

Research Areas:Cancer;Developmental Biology;Signal Transduction;Cardiovascular

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-hIgG1 Fc

UNIProt ID:O60462

Accession:O60462

Background:Neuropilins (NRPs) are single transmembrane receptors with short cytoplasmic tails and are dependent on receptors like VEGF receptors or Plexins for signal transduction. NRPs are known to be important in angiogenesis, lymphangiogenesis, and axon guidance. The Neuropilin-family consists of two members, Neuropilin-1 (NRP1) and Neuropilin-2 (NRP2). NRP2 is important for migration, antigen presentation, phagocytosis and cell-cell contact within the immune system. Additionally, posttranslational NRP2 modifications like polysialylation are crucial for the function of some immune cells.

Concentration:

Activity:Not validated for activity

Sequence:Val20-Glu855

Purity:> 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method

Calculated MW:116.9 kDa

ObservedMW:120 kDa