Recombinant Human Neuritin protein

SKU: CD01229

Size:5 ug

Background:Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. Recombinant human Neuritin is a 19.4 kDa, covalently disulfide-linked homodimer, consisting of two polypeptide monomers, each containing 88 amino acid residues.

Research_area:Others

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Neuritin

Biological activity:Fully biologically active when compared to standard. The ED5 as determined by by a cell proliferation assay using rat C6 cells is less than 25 ng/ml, corresponding to a specific activity of > 4. × 14 IU/mg.

Synonyms:NRN1,NRN, dJ38B8.2,Neuritin, Human

Endotoxin:Less than 0.1 EU/μg of rHuNeuritin as determined by LAL method.

Storage:-20ºC

Sequence:AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN

uniprot accession:Q9NPD7

Molecular weight:Approximately 19.4 kDa, a disulfide-linked homodimeric protein containing two 88 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered solution in PBS, pH 7.4.