Recombinant Human Immunoglobulin Superfamily Member 8/IGSF8/CD316 (C-Fc)

SKU: PKSH033946

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: Immunoglobulin

Target Synonym: IGSF;CD81 Partner;Immunoglobulin Superfamily Member;Glu-Trp-Ile EWI Motif-Containing Protein;Keratinocytes-Associated Transmembrane Protein;CD81P;LIR-D;EWI;KCT;IGSF8;CD316;CD81P3;EWI-2;EWI2;KCT-4;LIR-D1;PGRL;CD81 Partner 3;Glu-Trp-Ile EWI Motif-Containing Protein 2;Immunoglobulin Superfamily Member 8;Keratinocytes-Associated Transmembrane Protein 4;Prostaglandin Regulatory-Like Protein;KCT4; PGRL

Research Areas: Microbiology;Cancer;immunology

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc

UNIProt ID: Q969P0

Accession: Q969P0

Background: Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.

Concentration:

Activity: Not validated for activity

Sequence: Arg28-Thr579

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 85.7 kDa

ObservedMW: 90-120 kDa