Recombinant Human IL2RA Protein(Fc Tag)

SKU: PDMH100268

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:IL2RA

Target Synonym:Interleukin 2 receptor alpha chain;CD25;CD25 antigen;IDDM10;IL 2 receptor alpha subunit;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2 RA;IL2-RA;IL2R;IL2R;alpha chain;IL2RA;IL2RA;IMD41;Interleukin 2 receptor alpha;Interleukin 2 receptor;Interleukin-2 receptor subunit alpha;p55;t-cell growth factor receptor;TAC;TAC antigen;TCGFR

Research Areas:Cancer;Immunology

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-Fc

UNIProt ID:P01589

Accession:P01589

Background:The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with an the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with an interleukin 2 receptor alpha deficiency.

Concentration:

Activity:Not validated for activity

Sequence:Glu22-Gln240

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW: 48.9 kDa

ObservedMW:60 kDa