Recombinant Human IL18RAP/IL1R7 Protein (His Tag)

SKU: PKSH032568

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: IL18RAP;IL1R7

Target Synonym: IL1R;ACPL;CD218b;CDw218b;IL-18RAcP;IL18RB;IL-18Rbeta;IL-18R-beta;IL-1R7;IL-1R-7;IL-1RAcPL;IL1R7;IL18RAP; IL-1RcPL; CDw218b;IL18RβAccessory protein like;Accessory protein-like;CD218 antigen-like family member B;I18RA;IL 18RAcP;IL 1R accessory protein like;IL 1R7;IL 1RAcPL;IL-18 receptor accessory protein;IL18Rbeta;IL-1R accessory protein-like;Interleukin 18 receptor accessory protein;Interleukin-1 receptor 7;Interleukin-18 receptor accessory protein;Interleukin-18 receptor accessory protein-like;Interleukin-18 receptor beta;Interleukin-18 receptor beta chain

Research Areas: Cancer;immunology

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: O95256

Accession: O95256

Background: IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

Concentration:

Activity: Not validated for activity

Sequence: Phe20-Arg356

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 39.4 kDa

ObservedMW: 56 kDa