Recombinant Human IL-8 protein(GST tag)

SKU: PDEH100775

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:IL-8

Target Synonym:CXCL;Interleukin;C-X-C motif chemokine;Chemokine (C-X-C motif) ligand;IL8/CXCL;GCP;NAP;CXCL8;GCP-1;GCP1;IL8;LECT;LUCT;LYNAP;MDNCF;MONAP;NAF;NAP-1;NAP1;3-10C;AMCF-I;IL8/CXCL8;K60;Interleukin-8;IL-8;Emoctakin;C-X-C motif chemokine 8;Chemokine (C-X-C motif) ligand 8;Granulocyte chemotactic protein 1 (GCP-1);Monocyte-derived neutrophil chemotactic factor (MDNCF);(Ala-IL-8)77;(Ser-IL-8)72;9E3;Beta thromboglobulin like protein;CEF-4;chemokine;CXC motif;GCP/IL-8 protein I;GCP/IL-8 protein II;GCP/IL-8 protein III;GCP/IL-8 protein IV;GCP/IL-8 protein V;GCP/IL-8 protein VI;Granulocyte chemotactic protein 1;IL-8(1-77);IL-8(9-77);IL8/NAP1 form I;IL8/NAP1 form II;IL8/NAP1 form III;IL8/NAP1 form IV;IL8/NAP1 form V;IL8/NAP1 form VI;Inteleukin 8;ligand 8;Lymphocyte-derived neutrophil-activating factor;MDNCF-b;MDNCF-c;Monocyte-derived neutrophil chemotactic factor;Monocyte-derived neutrophil-activating peptide;Neutrophil activating peptide 1;Neutrophil activating protein 1;Neutrophil-activating factor;Neutrophil-activating protein 1;Protein 3 10C;Protein 3-10C;SCYB8;Small inducible cytokine subfamily B member 8;T cell chemotactic factor;T-cell chemotactic factor;TSG1

Research Areas:Cardiovascular,Immunology,Cancer

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-GST

UNIProt ID:P10145

Accession:P10145

Background:IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

Concentration:

Activity:Not validated for activity

Sequence:Ser28-Ser99

Purity: > 85% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:34.3 kDa

ObservedMW:9 kDa & 35 kDa