Recombinant Human IGF2BP2 Protein (His Tag, N-T7 Tag)

SKU: PKSH032557

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: IGF2BP2

Target Synonym: Hepatocellular Carcinoma Autoantigen p62;IGF-II mRNA-Binding Protein 2;IGF2 mRNA-Binding Protein 2;IGF2BP2;IMP-2;IMP2;Insulin-Like Growth Factor 2 mRNA-Binding Protein 2;VICKZ Family Member 2;VICKZ2

Research Areas: Signal Transduction;epigenetics and nuclear signal;immunology;metabolism;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-T7 & C-His

UNIProt ID: Q9Y6M1

Accession: Q9Y6M1

Background: Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Thr 220

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 27.2 kDa

ObservedMW: 43 kDa