Recombinant Human GM-CSF Protein(His Tag)

SKU: PDMH100207

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:GM-CSF

Target Synonym:Colony stimulating factor 2 (granulocyte-macrophage);Colony Stimulating Factor 2;Colony stimulating factor;Colony-stimulating factor;CSF 2;CSF;CSF2;CSF2;GM-CSF;GMCSF;Granulocyte Macrophage Colony Stimulating Factor;Granulocyte-macrophage colony-stimulating factor;MGC131935;MGC138897;MGI1GM;Molgramostin;Pluripoietin-a;Sargramostim

Research Areas:Immunology;Kits;Lysates;Other

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-His

UNIProt ID:P04141

Accession:P04141

Background:CSF2 (Colony Stimulating Factor 2) is a Protein Coding gene. Diseases associated with CSF2 include Mucositis and Candida Glabrata. Among its related pathways are RET signaling and IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. GO annotations related to this gene include cytokine activity and granulocyte macrophage colony-stimulating factor receptor binding. The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.

Concentration:

Activity:Not validated for activity

Sequence:AIa18-Glu144

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:13.9 kDa

ObservedMW:20-30 kDa