Recombinant Human GITR Ligand/TNFSF18 Protein(Fc Tag)

SKU: PDMH100335

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:GITR Ligand/TNFSF18

Target Synonym:UNQ;PRO;Tnfsf;Activation-inducible TNF-related ligand;Glucocorticoid-induced TNF-related ligand;hGITRL;TNLG2A;AITRL;GITRL;TL6;TNFSF18;UNQ149;PRO175;Activation inducible TNF related ligand;AITR ligand;AITR ligand|GITR ligand|glucocorticoid-induced TNFR-related protein ligand;GITR ligand;Glucocorticoid induced TNF related ligand;Glucocorticoid induced TNFR related protein ligand;MGC138237;TNF18;Tumor necrosis factor (ligand) superfamily member 18;Tumor necrosis factor ligand 2A;Tumor necrosis factor ligand superfamily member 18

Research Areas:Immunology;Tags & Cell Markers;Signal Transduction;Cancer;Cardiovascular

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-Fc

UNIProt ID:Q9UNG2

Accession:Q9UNG2

Background:The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thoμght to be important for interaction between T lymphocytes and endothelial cells.

Concentration:

Activity:Not validated for activity

Sequence:Glu52-Ser177

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:38.8 kDa

ObservedMW:40 kDa